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About Scripps Research

Scripps Research scientists are pursuing multiple lines of research aimed at understanding and helping to mitigate the impact of the novel coronavirus behind the COVID-19 pandemic. They are tracing how the virus originated and spreads, exploring how it invades the body and how the immune system responds, and working to develop potential vaccines and medicines against the virus. For the latest updates on COVID-19 from Scripps Research, visit scripps.edu/covid-19.

About the Andersen Lab at Scripps Research

The Andersen Lab at Scripps Research specializes in infectious disease genomics, using a combination of computational biology, experimentation and field work to better understand how pathogenic viruses emerge and cause large-scale outbreaks. Their research on COVID-19 uses genomic and other large-scale analyses to understand the spread and evolution of the pandemic, both locally in San Diego and globally.

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About UCSD

UCSD and UCSD Health are rapidly responding to the COVID-19 pandemic. Researchers and clinicians are generating new diagnostic capabilities, identifying therapeutic approaches and developing vaccines. Epidemiological studies are underway to understand transmission and limit community spread. For up-to-date information and to learn how you can support these efforts, visit campaign.ucsd.edu/impact/coronavirus/

About the Yeo Lab at UCSD

Gene Yeo is a Professor of Cellular and Molecular Medicine at the University of California, San Diego. The Yeo lab focuses on the regulation of RNA biology, engineering disease models and RNA therapeutics. Gene is affiliated with the UCSD graduate programs in Biomedical Sciences, Bioengineering, Neurosciences and Materials Sciences and Gene is also Co-Director of the Bioinformatics and Systems Biology Graduate Program and Scientific Director of the SCRM Genomics Core. The Yeo lab has previously published on host-virus interactions and is excited to utilize our functional genomics platforms to identify host regulators of COVID-19 permissiveness and develop RNA-targeting efforts.

About the Knight Lab at UCSD

Rob Knight is a Professor of Pediatrics, Bioengineering and Computer Science & Engineering, and Founding Director of the Center for Microbiome Innovation, at the University of California, San Diego. The Knight lab focuses on high-throughput microbiome science, including the Human Microbiome Project, the Earth Microbiome Project, and the American Gut Project (recently expanded internationally into the Microsetta Initiative, which we have already re-tooled to enable RNA sampling and processing). We are applying these techniques both to study the SARS-CoV-2 genome itself and to understand how the microbiome modifies susceptibility to viral infection and response to that infection in COVID-19 disease. We are particularly interested in understanding how modifiable factors such as diet and medications alter the microbiome in ways that can be used to combat COVID-19.

About the Laurent Lab at UCSD

The Laurent laboratory focuses on discovery of biomarkers for pregnancy complications, and has extensive experience with miniaturization and automation of genomic assays. For the SEARCH screening effort, the lab has set up an automated workflow for qRT-PCR to detect COVID-19 RNA, which has a capacity of over 3,000 tests per day.

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About Rady Children’s Hospital-San Diego

Rady Children’s Hospital-San Diego is a nonprofit, 524-bed pediatric-care facility dedicated to excellence in care, research and teaching. We are the only hospital in the San Diego area dedicated exclusively to pediatric healthcare and the region’s only designated pediatric trauma center. Rady Children’s Hospital is actively working on multiple projects to help and support children, families and community during the COVID-19 pandemic.

About Rady Children’s Institute for Genomic Medicine

Rady Children’s Institute for Genomic Medicine was founded as a non-profit organization in 2014 through a transformational pledge of $120 million from Ernest and Evelyn Rady. The Institute focuses on bringing rapid clinical diagnostics to support children with critical illness. The Institute is embedded within Rady Children’s Hospital-San Diego, and is leveraging its expertise and resources to support the COVID-19 response.